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Heart burn cure8/2/2023 However, 30% to 40% of people with symptoms assumed to be due to GERD still complain of heartburn and other GERD symptoms while taking PPIs, and little high-quality information has been available on why these symptoms persist despite treatment. PPIs are generally considered the best medical treatment for GERD. Patients with heartburn, the cardinal symptom of GERD, report reduced work productivity and significant impairments in health-related quality of life. One in five adults in the United States has GERD, with the annual costs for managing the disease estimated to exceed $12 billion. Hunter also serves as chief executive officer of the OHSU Health system in Portland, Oregon. “Should you actually have reflux disease, surgery is a better option than continued medication.” “If you are on medication for reflux and it is ineffective, rather than continuing the medication it makes sense to be tested,” said John Hunter, M.D., FACS, the study’s surgical principal investigator and professor of surgery in the Oregon Health & Science University School of Medicine. Those patients were entered into a randomized controlled trial, which tested an anti-reflux surgical treatment that turned out to be significantly more effective than proton-pump inhibitors, or PPIs, in addressing their heartburn. Of the 366 patients who were screened, only 78 could be positively identified as having heartburn that was GERD-related. ![]() ![]() The multisite study recruited patients from Veterans Affairs gastroenterology clinics throughout the nation. ![]() However, the new research suggests that many patients who are unresponsive to treatment by proton pump inhibitors, a standard set of medications prescribed to stop excess acid production in the stomach for conditions such as GERD, never had the disease in the first place.įurthermore, among the patients who do have GERD, and for whom medication doesn’t effectively relieve their heartburn, the study found that surgery is a better course of action than continued therapy with medication. Heartburn is the most commonly reported symptom of the disease. Research published in The New England Journal of Medicine suggests a new course of diagnosis and treatment for the estimated one in five adults with symptoms of gastroesophageal reflux disease, or GERD.
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